BDBM50060417 5-Methyl-3,5-dihydro-2H-pyrrolo[2,3-f]indole-1-carboxylic acid pyridin-3-ylamide::CHEMBL297784::SB 206553::SB-206553

SMILES Cn1ccc2cc3N(CCc3cc12)C(=O)Nc1cccnc1

InChI Key InChIKey=QJQORSLQNXDVGE-UHFFFAOYSA-N

Data  30 KI  6 IC50  2 EC50

  Tab Delimited (TSV)   2D SDfile   Computed 3D by Vconf -m prep SDfile
Find this compound or compounds like it in BindingDB:
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Similarity at least:  must be >=0.5
Exact match

Activity Spreadsheet -- Enzyme Inhibition Constant Data from BindingDB

Found 7 hits for monomerid = 50060417   

Target5-hydroxytryptamine receptor 2B(RAT)
Smithkline Beecham Pharmaceuticals

Curated by PDSP Ki Database
LigandPNGBDBM50060417(5-Methyl-3,5-dihydro-2H-pyrrolo[2,3-f]indole-1-car...)
Affinity DataKi:  1.29nMMore data for this Ligand-Target Pair
In DepthDetails ArticlePubMed
Target5-hydroxytryptamine receptor 2B(Homo sapiens (Human))
University Of North Carolina At Chapel Hill

Curated by ChEMBL
LigandPNGBDBM50060417(5-Methyl-3,5-dihydro-2H-pyrrolo[2,3-f]indole-1-car...)
Affinity DataKi:  4.30nMAssay Description:Displacement of [3H]LSD from human cloned 5HT2B receptor expressed in CHO cells by liquid scintillation countingMore data for this Ligand-Target Pair
In DepthDetails ArticlePubMed
Target5-hydroxytryptamine receptor 2B(Homo sapiens (Human))
University Of North Carolina At Chapel Hill

Curated by ChEMBL
LigandPNGBDBM50060417(5-Methyl-3,5-dihydro-2H-pyrrolo[2,3-f]indole-1-car...)
Affinity DataKi:  5.5nMMore data for this Ligand-Target Pair
In DepthDetails ArticlePubMed
Target5-hydroxytryptamine receptor 2B(Homo sapiens (Human))
University Of North Carolina At Chapel Hill

Curated by ChEMBL
LigandPNGBDBM50060417(5-Methyl-3,5-dihydro-2H-pyrrolo[2,3-f]indole-1-car...)
Affinity DataKi:  20nMAssay Description:Displacement of [3H]LSD from 5-HT2B receptor (unknown origin) assessed as inhibition constant incubated for 90 mins by MicroBeta scintillation counti...More data for this Ligand-Target Pair
In DepthDetails PubMed
Target5-hydroxytryptamine receptor 2B(Homo sapiens (Human))
University Of North Carolina At Chapel Hill

Curated by ChEMBL
LigandPNGBDBM50060417(5-Methyl-3,5-dihydro-2H-pyrrolo[2,3-f]indole-1-car...)
Affinity DataKi:  22.4nMMore data for this Ligand-Target Pair
In DepthDetails ArticlePubMed
Target5-hydroxytryptamine receptor 2B(Homo sapiens (Human))
University Of North Carolina At Chapel Hill

Curated by ChEMBL
LigandPNGBDBM50060417(5-Methyl-3,5-dihydro-2H-pyrrolo[2,3-f]indole-1-car...)
Affinity DataKi:  25nMAssay Description:Binding affinity towards cloned human 5-hydroxytryptamine 2B receptor expressed in HEK 293 cells using [3H]5-HT as radioligandMore data for this Ligand-Target Pair
In DepthDetails ArticlePubMed
Target5-hydroxytryptamine receptor 2B(Homo sapiens (Human))
University Of North Carolina At Chapel Hill

Curated by ChEMBL
LigandPNGBDBM50060417(5-Methyl-3,5-dihydro-2H-pyrrolo[2,3-f]indole-1-car...)
Affinity DataEC50:  13nMAssay Description:Antagonist activity at recombinant human 5-HT2B receptor expressed in CHOK1 cells assessed as inhibition of serotonin-induced increase in inositol1-p...More data for this Ligand-Target Pair
In DepthDetails ArticlePubMed